Human Evolutionary Genetics
19.10.2017 - 09.02.2018
Prof. Dr. Wolfgang Enard
Dr. Noemie Becker
Dr. Sonja Grath
This seminar discusses new and classical papers about how and when human populations evolved. Each week, two students are assigned a topic for a 15 minutes presentation. The topics are related to the article discussed that week but should not be based on the article only. Everyone else is expected to read the paper and contribute to the discussion.
- Human Biology
- nbecker AT bio.lmu.de
- grath AT bio.lmu.de
3 ECTS, 2 SWS
Please be aware that we moved the starting time back to 8:30!
Every week, Thursday, 8:30-10:00
You will get an ungraded certificate (pass/fail) for the course.
To successfully pass the course, you have to:
- Attend all seminars: We allow one 'joker'. Make sure that you sign the attendance sheet each week.
- Give a presentation
- Be active in the discussions
In case your program requires you to get a graded certificate, please inform the instructors at the beginning of the course.
to the requirements above, if you need a graded certificate, you have to:
- Write a short essay (3-4 pages) on the topic of your presentation
- You final grade will be based on both your presentation and the essay.
You can download the course syllabus here
: How to read a scientific paper
: How to (seriously) read a scientific paper
Program (Winter Semester 2017/18)
Session 1 (Oct 19, 2017): Introduction (by the lecturers)
Session 2 (Oct 26, 2017): Mitochondrial Eve
- Introduction of the main concepts of human evolutionary genetics;
: Mitochondrial DNA and human evolution. Cann, Stoneking and Wilson (1987), Nature.
: Interview with R. Cann: All about mitochondrial Eve. Glitschier (2010), PLoS Genetics.
Session 3 (Nov 2, 2017): Y haplotypes
: Y haplotypes. Seidelstad et al. (1999), Genome Research.
Session 4 (Nov 9, 2017): Actual datasets - The explosion of human data in the last 10 years
: A map of human genome variation from population-scale sequencing. The 1000 Genomes Consortium (2010), Nature.
: Christopher, Amit
Session 5 (Nov 16, 2017): Measures of population structure
: Genetic Structure of Human Populations. Rosenberg et al. (2002), Science.
: Zane, Andres
Session 6 (Nov 23, 2017): Genes mirror geography
: Genes mirror geography within Europe. Novembre et al. (2008), Nature.
: Alexandra, Cara
Session 7 (Nov 30, 2017): Speciation
: Insights into hominid evolution from the gorilla genome sequence. Scally et al. (2012), Nature.
: Dorothy, Melanie
Session 8 (Dec 7, 2017): Reconstructing evolution through linguistics
: Bantu language trees reflect the spread of farming across sub-Saharan Africa: a maximum-parsimony analysis. Holden (2002), Proc. R. Soc. Lond. B.
: Ismail, Samuel
Session 9 (Dec 14, 2017): Detecting positive selection in human populations
: Positive natural selection in the human lineage. Sabeti et al. (2006), Science.
: Katharina, Pia-Maria
Session 10 (Dec 21, 2017): Immunology/Medical genetics
: The Major Genetic Determinants of HIV-1 Control Affect HLA Class I Peptide Presentation. International HIV Controllers Study. Science, 2010.
Session 11 (Jan 11, 2018): Epigenetics
: A twin approach to unraveling epigenetics. Bell and Spector. Tends Genetics, 2011.
: Olivia, Tim
Session 12 (Jan 18, 2018): Anthropometrics
: From Preferred to Actual Mate Characteristics: The Case of Human Body Shape. Courtiol et al. (2010), PLoS ONE.
Session 13 (Jan 25, 2018): Ancient DNA
: Nuclear and mitochondrial DNA sequences from two Denisovan individuals. Sawyer et al. (2015) PNAS.
: Elisabeth, Lara
Session 14 (Feb 1, 2018): Ethics questions
As background for this session, please read the 2 Opinion articles on the question: Should scientists study race and IQ?
And the following article
: Implications of biogeography of human populations for 'race' and medicine. Tishkoff and Kidd (2004), Nature Genetics.
: Janina, Paula
Session 15 (Feb 8, 2018): Conclusion (by the lecturers)